Skin & Hair
MT-II Explained
Dr. E. Halvorsen·2025-11-14· 5 min read
Melanotan II (MT-II) is a cyclic synthetic analog of α-melanocyte-stimulating hormone. It binds non-selectively across MC1R, MC3R, MC4R and MC5R receptors.
MC1R engagement drives melanogenesis in melanocytes; MC4R modulation is linked to central appetite pathways. This receptor promiscuity is both its research value and its complication — data must be interpreted carefully.
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